cold agglutinin sentence in Hindi
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- The cold agglutinin detected is of anti-i specificity.
- This is the case in both cold agglutinin disease and cold paroxysmal hematuria.
- Individuals with cold agglutinin disease present with signs and symptoms of hemolytic anemia.
- There are also reports of eculizumab being used to treat cold agglutinin disease.
- Cold agglutinins, or cold autoantibodies, occur naturally in nearly all individuals.
- In individuals that have cold agglutinin disease, the lifespan of erythrocytes is shortened.
- In chronic cold agglutinin disease, the patient is more symptomatic during the colder months.
- Rheumatoid factor, cryoglobulins, direct antiglobulin test and cold agglutinin titre results can be positive.
- This is seen in Waldenstr�m's macroglobulinemia, cold agglutinin disease and Infection with Mycoplasma Pneumonia.
- Tests revealed no structural heart defects, and after some deliberations the possibility of cold agglutinin disease is raised.
- Agglutinin might also be associated with diseases of which the most common is an autoimmune disease known as cold agglutinin disease.
- A common complaint among patients with cold agglutinin disease is painful fingers and toes with purplish discoloration associated with cold exposure.
- In cold agglutinin disease, the body produces agglutinins or antibodies that coagulate erythrocytes and lyse them at room temperature or lower.
- Pathologic cold agglutinins occur at titers over 1 : 1000 and react at 28-31 �C and sometimes at 37 �C.
- Cold agglutinins commonly have variable heavy-chain regions encoded by VH, with a distinct idiotype identified by the 9G4 rat murine monoclonal antibody.
- House notices that the patient's blood thickens dangerously when his body temperature drops ( cold agglutinin disease ), something that cannot be faked.
- The rate of erythrocyte production by the bone marrow is lower than the rate of destruction, thus, individuals with cold agglutinin disease develop a form of anemia.
- Mononucleosis is sometimes accompanied by secondary cold agglutinin disease, an autoimmune disease in which abnormal circulating antibodies directed against red blood cells can lead to a form of autoimmune hemolytic anemia.
- Cold agglutinin disease usually results from the production of a specific IgM antibody directed against the I / i antigens ( precursors of the ABH and Lewis blood group substances ) on red blood cells ( RBCs ).
- "' Cryoglobulinemia "'or "'cryoglobulinaemia "'is a medical condition in which the blood contains large amounts of cryoglobulins proteins ( mostly cold agglutinins, which cause agglutination of red blood cells.
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